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Allografts
can be considered a useful option for reconstruction with no significant
complications in the surgical treatment of foot and ankle.
Recently,
a piece of evidence was found favouring the use of allografts in lateral ankle
ligament reconstruction or treatment of intra-articular calcaneal fracture,
depicted in a review published in journal 'Knee surgery, sports traumatology,
arthroscopy'.
This review aimed to systematically analyse the present literature on the use
of allografts in the surgical treatment of foot and ankle conditions in adult
patients.
As per this, the evidence-based recommendations were proposed by
Diniz P et al.
PubMed was searched for all published articles with no timeframe restrictions.
The inclusion criteria were based on: considering patients over 18 years old;
subject to the surgical treatment of foot and ankle conditions; with a report
on the outcome of the use of allografts; with a report and assessment of pain
and function, or equivalent; with a minimum follow-up of 1 year. Two reviewers
independently screened and picked up studies for the full-text analysis from
title and abstract. Total of 107 studies was included from 1113 records. Ten
categories were made as per the studies grouped as per surgical indications:
musculoskeletal tumours (n = 16), chronic ankle instability (CAI)
(n = 15), ankle arthritis (n = 14), osteochondral lesions of the talus (n = 12),
Achilles tendon defects (n = 11), other tendon defects (n = 9), fusions (n = 9),
fractures (n = 8), hallux rigidus (n = 3) and other indications (n = 10). Most
of the studies revealed the evidence level of IV (n = 57) and V (n = 39). There
was one level I, one level II and nine level III studies, respectively. Also,
many studies described allografting as a good option with an overall
complication rate of just 17% (n = 202).
The study authors concluded, " Fair evidence (Grade B) was found against
the use of allogeneic MSCs in tibiotalar fusions."
Knee surgery, sports traumatology, arthroscopy
Clinical applications of allografts in foot and ankle surgery
Diniz P et al.
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