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Corticosteroids may provide greater postoperative
endodontic pain relief than placebo in
patients with symptomatic pulpitis going through root-canal.
As per a recent systematic review and meta analysis results
published in the Journal of Endodontics, the corticosteroids found effective
than placebo in relieving postoperative endodontic pain following single-visit
root canal treatment (RCT). Dental pain a common problem in the general
population, and many individuals may feel anxiety while attending dental
appointments due to fear of pain at the time of surgeries. Various approaches
have been used to provide relief from pain following RCT and out of them is
corticosteroids.
The study aimed to evaluate the corticosteroids effectiveness in reducing postoperative pain and related side effects after dental surgery as compared to placebo or other analgesics. Scopus, Cochrane, Medline and PubMed database was searched to find the related published articles. Clinicaltrials.gov site was also searched. Two independent reviewers estimated the quality, extracted data and eligibility for inclusion. The pooled effect size was used to perform the meta-analysis.
A total of 37 citations via manual and 481 via database
search was selected. Only 28 full-text articles were left after removing the
duplicates. Out of 28, the inclusion criteria were completed by the five
articles. One study has a low risk of bias, and four had the unclear risk of
bias as per qualitative analysis — left articles presented with lesser sample
size. The Prednisolone delivered before the treatment was capable of reducing
postoperative pain at 6 h, 12 h and one day. No adverse effects were noticed
during the analysis. These findings reflected a positive role of
corticosteroids in postoperative dental pain management; however further
research with large sample sizes is required to validate the outcomes.
Journal of Endodontics
Effect of Preoperative Corticosteroids in Patients with Symptomatic Pulpitis on Postoperative Pain after Single-visit Root Canal Treatment: A Systematic Review and Meta-analysis
Chinni Suneelkumar et al.
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