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Methotrexate remains the choice of treatment for RA
patients as it significantly reduced inflammation, disease activity and risk of
cardiovascular disease in patients with RA.
Overall, the results were conclusive that MTX can be a safe
and effective for the treatment of RA. The liver function test of RA patients
was normal but patients experienced disturbances in mineral accumulation, suggesting
the need for mineral evaluation and supplementation, especially of magnesium in
RA patients. The treatment was helpful in reducing inflammation and the
activity of the disease and was effective for lipid parameters that in turn
reduce the risk of cardiovascular disease.
Current Orthopaedic Practice
Methotrexate as effective and safe choice for the treatment of rheumatoid arthritis
Kumar et al.
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