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This study was conducted to compare the efficacy of epidural ropivacaine with and without dexmedetomidine on postoperative pain relief after the thoracolumbar spine instrumentation.
Given the safety and efficacy of
dexmedetomidine, the decreased rescue analgesia usage, enhanced analgesia
period, and decreased pain scores, this study portrayed a combination of
epidural ropivacaine and dexmedetomidine to be more effective for the
thoracolumbar spine than ropivacaine alone.
This study was conducted to compare the efficacy
of epidural ropivacaine with and without dexmedetomidine on postoperative pain
relief after the thoracolumbar spine instrumentation.
Overall, 60 adult subjects (age group of 18-65 years) who were planned to undertake thoracolumbar spine instrumentation were allocated to either Group RD (epidural ropivacaine plus dexmedetomidine) or Group R (epidural ropivacaine plus saline).
The total rescue analgesic usage on days 0, 1, and 2 of the operation were compared. Total patient satisfaction scores and time to first rescue analgesia via the VAS score <4 were examined.
No change between the demographic features of the two groups was found. The mean value of total rescue analgesia usage, mean time to first rescue analgesia, and mean patient satisfaction score RD group and R group as shown in the following Table 1:
During the postoperative phase, no patient
exhibited any respiratory depression or sustained motor blockade.
In patients experiencing surgery for
thoracolumbar spine, epidural ropivacaine plus dexmedetomidine displayed
superior efficacy concerning postoperative pain relief and patient satisfaction
scores as compared to ropivacaine alone.
Emergency Medicine Journal: EMJ
Influence of Epidural Ropivacaine with or without Dexmedetomidine on Postoperative Analgesia and Patient Satisfaction after Thoraco-Lumbar Spine Instrumentation: A Randomized, Comparative, and Double-Blind Study
Faisal Qureshi et al.
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