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A parallel, double‐blind, randomized, and short‐term (7-day) study was carried to explore the anti-gingivitis and anti-plaque efficacy in addition to assessing adverse effects and participants’ perceptions of the available mouthwashes.
Chlorhexidine is the most effective antiplaque mouthwash
although antioxidants and hyaluronic acid are as effective as chlorhexidine in
minimizing bleeding. Based on hyaluronic acid's better acceptance by
individuals, it seems to be a promising alternative to chlorhexidine.
A parallel, double‐blind,
randomized, and short‐term (7-day) study was carried to explore the anti-gingivitis
and anti-plaque efficacy in addition to assessing adverse effects and
participants’ perceptions of the available mouthwashes.
The study incorporated 75 dental students having
biofilm‐induced gingivitis. The staining effect and clinical parameters like
plaque index and bleeding on probing were estimated at baseline and after seven
days. Furthermore, a visual analogue scale (VAS)‐based assessment questionnaire
was completed by the enrolled subjects. Any potential side effects were evaluated
by examining staining and evaluation of participants’ feedback for the three
commercially available mouthwashes utilized.
All the interventions considerably minimized the plaque scores. However, chlorhexidine displayed remarkably better effect compared to the hyaluronic acid and antioxidant mouthwashes.
In
comparison with the baseline record, all the mouthwashes remarkably lowered the
total bleeding scores to <10% in 53% of the subjects. Furthermore, the teeth
underwent shade alterations in relation to all the interventions by the end of
the analysis. Assessment of feedback about the mouthwashes demonstrated that
the individuals prefer the hyaluronic acid mouthwash when compared to the other
mouthwashes.
Hyaluronic acid mouthwash is a good alternative to
chlorhexidine mouthwash as it has a better acceptance rate.
International Journal of Dental Hygiene
A randomized double-blind clinical trial to evaluate the efficacy of chlorhexidine, antioxidant, and hyaluronic acid mouthwashes in the management of biofilm-induced gingivitis
Ali A Abdulkareem et al.
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