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This study examined the influence of ramosetron on the recovery of bowel function following gynecological laparoscopic surgery.
Following gynecologic laparoscopic surgery, the
bowel movement recovery was not delayed by ramosetron. Moreover, ramosetron
showed comparable efficacy as dexamethasone in the regulation of postoperative
nausea and vomiting.
This study examined the influence of ramosetron
on the recovery of bowel function following gynecological laparoscopic surgery.
In this prospective randomized controlled trial,
the recruited people (n=88) were randomly allocated to get either 10 mg dexamethasone prior to
anesthesia initiation (Control group), followed by intravenous administration
of patient-controlled analgesia (IV-PCA) or 2 ml normal saline prior to
anesthesia initiation and 0.6 mg ramosetron (Study group) given with IV-PCA.
Regarding the time to first flatus and the time to first defecation, no profound differences were noted.
Also, there were no considerable differences in the demand for additional analgesic agents and the frequency of postoperative nausea and vomiting (PONV). Multiple linear regression for assessment of factors influencing the time to first flatus exhibited no substantial outcomes.
Ramosetron did not hinder the recovery of bowel
motility following gynecologic laparoscopic surgery and was as efficacious as
dexamethasone in managing PONV. Ramosetron can be utilized with IV-PCA without
worrying about the delay in the restoration of bowel function.
The International Journal of Gynecology & Obstetrics
A randomized controlled trial of the effect of ramosetron on postoperative restoration of bowel motility after gynecologic laparoscopic surgery
Hee Yong Kang et al.
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