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Preemptive pain management in single dental implant surgery

Single dental implant surgery Single dental implant surgery
Single dental implant surgery Single dental implant surgery

To study the efficacy of preemptive analgesia in single dental implant surgeries and find which among four analgesic agents - Etoricoxib (ETOR), Ibuprofen (IBU), Nimesulide (NIME), and Acetaminophen (ACETA) is effective for mitigating postoperative pain and decreasing the need for rescue medication.

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Key take away

Etoricoxib shows superior effectiveness in reducing postoperative pain compared to other analgesic agents in single dental implant procedures.

Background

To study the efficacy of preemptive analgesia in single dental implant surgeries and find which among four analgesic agents - Etoricoxib (ETOR), Ibuprofen (IBU), Nimesulide (NIME), and Acetaminophen (ACETA) is effective for mitigating postoperative pain and decreasing the need for rescue medication.

Method

Overall, 135 participants [mean age of 57.6 years (±11.7)] participated in this randomized controlled clinical trial. They were randomly allocated into five groups based on the administered drug: I-PLACEBO; II-IBU (dosed at 600 mg); III-NIME (dosed at 100 mg); IV-ACETA (dosed at 750 mg); and V-ETOR (dosed at 90 mg). Chi-square, Fisher's exact, and ANOVA were used to assess pain (occurrence, duration, and severity), along with generalized estimating equation models as needed.

Result

These therapeutic agents delivered a decrease in postoperative pain scores and illustrated a lesser need for rescue medication than with placebo. The ETOR group displayed significantly lower pain scores when contrasted with the other active treatment groups. Conversely, the IBU group had the highest average number of rescue medications consumed.

Conclusion

All of the therapies under consideration illustrated a beneficial preemptive effect, evidenced by the reduction in postoperative pain and diminished use of rescue therapies.

Source:

Clinical Oral Implants Research

Article:

Preemptive effects of etoricoxib, acetaminophen, nimesulide, and ibuprofen on postoperative pain management after single-implant surgery: A randomized clinical trial

Authors:

Gustavo Henrique Mattos-Pereira et al.

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