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A multicentre study was performed to assess the effectiveness of SBRT for painful non-spine bone metastases.
From a recent study, it
was found that the stereotactic body radiotherapy (SBRT) for non-spine bone
metastases was successful in providing the pain palliation. The results from
this study demanded a larger RCT trial to evaluate SBRT in comparison with
conventional radiotherapy.
A multicentre study was
performed to assess the effectiveness of SBRT for painful non-spine bone
metastases.
In this study, patients
suffering from painful non-spine bone metastases were included. They were given
a dose of 35 Gy in five parts. The major outcome was the pain response rate
calculated six months following the SBRT.
There were 41osseous lesions reported in thirty-eight patients. Patients were suffering mostly from lung cancer. The percentage of sufferers with uterus cancer, prostate cancer and renal cell carcinoma was comparatively less. The bone metastases were mostly found in coxal bones.
The median length of follow-up following the check was eight months. Amongst the lesions, which were able to be evaluated at 3 and 6 months following the SBRT, the pain response rates were 78% and 75%, at 3-month and 6-month correspondingly.
SBRT in the treatment of
non-spine bone metastases relieved the pain.
Practical Radiation Oncology
Phase II clinical trial of stereotactic body radiotherapy for painful non-spine bone metastases
Kei Ito et al.
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