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Allografts proved beneficial in foot and ankle surgery

Allografts proved beneficial in foot and ankle surgery Allografts proved beneficial in foot and ankle surgery
Allografts proved beneficial in foot and ankle surgery Allografts proved beneficial in foot and ankle surgery

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Allografts can be considered a useful option for reconstruction with no significant complications in the surgical treatment of foot and ankle.

Recently, a piece of evidence was found favouring the use of allografts in lateral ankle ligament reconstruction or treatment of intra-articular calcaneal fracture, depicted in a review published in journal 'Knee surgery, sports traumatology, arthroscopy'.
This review aimed to systematically analyse the present literature on the use of allografts in the surgical treatment of foot and ankle conditions in adult patients.

As per this, the evidence-based recommendations were proposed by Diniz P et al.
PubMed was searched for all published articles with no timeframe restrictions. The inclusion criteria were based on: considering patients over 18 years old; subject to the surgical treatment of foot and ankle conditions; with a report on the outcome of the use of allografts; with a report and assessment of pain and function, or equivalent; with a minimum follow-up of 1 year. Two reviewers independently screened and picked up studies for the full-text analysis from title and abstract. Total of 107 studies was included from 1113 records. Ten categories were made as per the studies grouped as per surgical  indications:  musculoskeletal tumours (n = 16), chronic ankle instability (CAI) (n = 15), ankle arthritis (n = 14), osteochondral lesions of the talus (n = 12), Achilles tendon defects (n = 11), other tendon defects (n = 9), fusions (n = 9), fractures (n = 8), hallux rigidus (n = 3) and other indications (n = 10). Most of the studies revealed the evidence level of IV (n = 57) and V (n = 39). There was one level I, one level II and nine level III studies, respectively. Also, many studies described allografting as a good option with an overall complication rate of just 17% (n = 202).

The study authors concluded, " Fair evidence (Grade B) was found against the use of allogeneic MSCs in tibiotalar fusions."

Source:

Knee surgery, sports traumatology, arthroscopy

Article:

Clinical applications of allografts in foot and ankle surgery

Authors:

Diniz P et al.

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