Categories
Change Password!
Reset Password!
Both Hyoscine butyl-bromide and Ondansetron are effective in combating nausea and vomiting during cesarean deliveries.
A recent study published in the “Egyptian Journal of Anaesthesia” compared two medications for preventing nausea and vomiting during cesarean deliveries performed under spinal anesthesia. The trial pitted Hyoscine butyl-bromide (HBB) against Ondansetron, two drugs known for their anti-nausea properties.
In women who were scheduled to undergo a cesarean section with spinal anesthesia, the use of prophylactic HBB was found to be equally effective as Ondansetron in minimizing intraoperative vomiting. Additionally, HBB had the advantage of causing a lower occurrence of intraoperative bradycardia compared to Ondansetron. On the other hand, Ondansetron remarkably reduced postoperative nausea and vomiting (PONV) occurrence.
Mostafa Samy Abbas et al. performed this randomized, double-blind, placebo-controlled trial, which included 55 participants undergoing elective caesarean delivery. They were assigned to receive either intravenous HBB (20 mg), Ondansetron (8 mg), or a saline placebo (0.9%) just before spinal anaesthesia. The key endpoint of the study was to determine the occurrence of intraoperative nausea and vomiting (IONV). Secondary objectives included examining instances of maternal bradycardia and hypotension during surgery, as well as assessing PONV.
Below are the major findings of the study:
These findings mark a huge leap in improving the experience of expectant mothers undergoing cesarean deliveries. The study's insights into the efficacy and safety of these medications hold promising outcomes for maternal care during childbirth.
Egyptian Journal of Anaesthesia
Hyoscine butyl-bromide versus ondansetron for nausea and vomiting during caesarean delivery under spinal anaesthesia. A randomized clinical trial
Mostafa Samy Abbas et al.
Comments (0)