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Study assesses efficacy of Buprenorphine + Local anesthetic solution for postoperative dental pain

Third molar extraction therapy Third molar extraction therapy
Third molar extraction therapy Third molar extraction therapy

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Administration of a local anesthetic solution (2% Lignocaine with Adrenaline) combined with Buprenorphine for intraoral block related procedures significantly reduces pain following surgical extraction of mandibular third molar.

A prospective, randomized controlled study depicted that a combination of local anesthetic solution and Buprenorphine during intraoral block procedures was an effective and safe pain management approach. Researchers aimed to compare Buprenorphine and 2% Lignocaine with Adrenaline in providing postsurgical pain relief after mandibular third molar extraction.

The study enrolled a total of 40 participants, who were randomized to either Group A or Group B, with 20 subjects in each group. For inferior alveolar nerve block, Group A was given a combination of 2% Lignocaine with 1:80,000 Adrenaline and Buprenorphine, while Group B was administered 2% Lignocaine with 1:80,000 Adrenaline.

The data was gathered and entered into a Microsoft Excel spreadsheet, then analyzed using SPSS software, version 21. The data was compared using Student's t-test, with a significance level set at 0.05. The combination of a local anesthetic solution and Buprenorphine was promising in the induction of postoperative analgesia without significant side effects in individuals undergoing molar extraction surgery.

Source:

Journal of Advanced Medical and Dental Sciences Research

Article:

A comparative study to appraise the efficiency of Buprenorphine and 2% Lignocaine with Adrenaline in induction of post operative analgesia following surgical extraction of mandibular third molar

Authors:

Maroofa Hafiz et al.

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