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A study was conducted to determine efficacy of magnesium sulphate + bupivacaine for arthroscopy.
For conducting arthroscopy, combination analgesia with magnesium
sulphate plus bupivacaine offers better alleviation of pain when compared to
bupivacaine alone.
A study was conducted to determine efficacy of magnesium sulphate + bupivacaine
for arthroscopy.
In this systematic review and meta-analysis, databases like Embase, Cochrane Library, PubMed, EBSCO, and Web of science were explored for the relevant randomized controlled trials (RCTs) that determined the effect of magnesium sulphate + bupivacaine vs bupivacaine for arthroscopy.
A random-effect model was used for carrying out this meta-analysis. Pain scores
and duration of analgesia were the primary endpoints while analgesic
consumption, first time to analgesic need, and nausea and vomiting were the
secondary endpoints.
Overall, 6 RCTs were incorporated. In comparison with bupivacaine
alone, magnesium sulphate in combination with bupivacaine was linked with
considerably extended duration of analgesia (standard mean difference [SMD] = 0.93) and
first time to analgesic need (SMD=196.57), decreased pain scores (SMD=-1.71)
and minimized analgesic consumption (SMD=-1.04). However, no significant
influence was noted on nausea or vomiting (OR=1.54).
Magnesium sulphate in combination with bupivacaine
can substantially enhance the pain-relieving effectiveness for arthroscopy.
The Journal of Orthopaedic Surgery and Research
The effect of magnesium added to bupivacaine for arthroscopy: a meta-analysis of randomized controlled trials
Weineng Xiang et al.
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