A study was carried out to explore the pain-relieving advantages of lidocaine infiltration for abdominal hysterectomy.
In people undergoing abdominal
hysterectomy, intraperitoneal instillation of lidocaine is safe, feasible,
cheap, and is associated with effective analgesia in terms of decreased
postsurgery pain scores and morphine intake.
A study was carried out to explore
the pain-relieving advantages of lidocaine infiltration for abdominal
hysterectomy.
In this systematic review and
meta-analysis of randomized placebo-controlled clinical trials, an inspection
of 5 electronic databases was done (from inception up to 5 August 2021).
Evaluation of the eligible randomized trials was done for the risk of biasness.
The pooled outcomes were summarized as mean difference (MD) or risk ratio (RR).
Overall, 5 randomized controlled trials (RCTs) fulfilled the inclusion criteria comprising 263 participants (119 and 117 people were assigned to lidocaine group and control group, respectively). The incorporated RCTs showed a low risk of bias. The postsurgery pain scores at rest were considerably reduced in favor of the lidocaine group (MD=-1.01), and subgroup assessment showed the same at two, four, eight, 12, 24, and 48 hours after surgery.
Furthermore, the postsurgery pain scores at moving were considerably reduced in
favor of the lidocaine group (MD=-0.67), and subgroup assessment showed the
same at two and 48 hours after surgery. The postsurgery morphine intake during
0-24 hours (n = 5 RCTs, MD=-7.29 mg) and the rate of postsurgery vomiting (n =
4 RCTs, RR=0.54) was remarkably reduced in favor of the lidocaine group.
Lidocaine
administered via the
intraperitoneal route offers remarkable pain-relieving benefits in patients
undergoing abdominal hysterectomy.
Journal of Gynecology Obstetrics and Human Reproduction
Intraperitoneal lidocaine instillation during abdominal hysterectomy: A systematic review and meta-analysis of randomized placebo-controlled trials
Ahmed Abu-Zaid et al.
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