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Comparison of Nasal High-flow Oxygen and Conventional Oxygen Therapy in asthma patients

Comparison of Nasal High-flow Oxygen and Conventional Oxygen Therapy in asthma patients Comparison of Nasal High-flow Oxygen and Conventional Oxygen Therapy in asthma patients
Comparison of Nasal High-flow Oxygen and Conventional Oxygen Therapy in asthma patients Comparison of Nasal High-flow Oxygen and Conventional Oxygen Therapy in asthma patients

This pilot study aimed to compare the effectiveness of nasal high flow (NHF) and conventional oxygen therapy (COT) in the improvement of dyspnea (shortness of breath) in acute severe asthma in the emergency department.      

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Key take away

This randomized controlled study found the use of nasal high flow therapy to be advantageous over conventional oxygen therapy in terms of providing respiratory support and oxygenation in adults with severe asthma and lower oxygen levels in the emergency ward.

Background

This pilot study aimed to compare the effectiveness of nasal high flow (NHF) and conventional oxygen therapy (COT) in the improvement of dyspnea (shortness of breath) in acute severe asthma in the emergency department.      

Method

Thirty-seven patients aged ≥ 18 years with acute severe asthma and lower oxygen levels than normal (hypoxemia) were recruited. These patients were arbitrarily allotted to receive either COT (18 patients) or NHF (19 patients) for 2 hours.

Comparison of effects of the interventions used on the degree of dyspnea evaluated via the modified Borg scale (MBS) was the primary outcome. Comparisons of the numeric rating scale (NRS) of dyspnea, the dyspnea scale evaluating accessory muscle use, vital signs, and blood gas outcomes comprised of secondary outcomes.

Result

The intention-to-treat analysis encompassed 37 patients. Both groups had a baseline mean MBS of 7.8. The mean MBSs in patients receiving COT and NHF were 3.3 and 1.4, respectively at 120 minutes.

Similar trends followed in NRS and dyspnea score results to those of MBS. There were lower respiratory rates with the use of NHF. No between- or in-group differences in blood gas outcomes were noted.

Conclusion

NHF proved to be efficacious in decreasing the severity of dyspnea and respiratory rate in hypoxemic adult patients with asthma.

Source:

Academic Emergency Medicine

Article:

Nasal High-flow Oxygen Versus Conventional Oxygen Therapy for Acute Severe Asthma Patients: A Pilot Randomized Controlled Trial

Authors:

Onlak Ruangsomboon et al.

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