A study was performed to describe the occurrence and outcomes of coronavirus-infected patients who needed positive pressure ventilation (PPV) and ultimately develop PBT.
This observational case-control study confirmed
the occurrence of pulmonary barotrauma (PBT) in 60 out of 1095 critically ill
SARS-CoV-2 infected adults, thereby portraying a high risk of PBT in these
patients.
A study was performed to describe the occurrence
and outcomes of coronavirus-infected patients who needed positive pressure
ventilation (PPV) and ultimately develop PBT. Furthermore, the predictors and
risk factors of these complications were explored to decipher the pathogenesis
of the disease.
Adult hospitalized COVID-19 patients aged ≥ 18
years who received any type of PPV were included. In this retrospective
analysis, patients were then stratified into groups as per the development of
PBT, comprising subcutaneous emphysema, collapsed lung, and pneumomediastinum.
A review of the medical history of all the subjects was done. Demographics and
lab data of the patient, surgical interventions, mechanical ventilation modes,
and outcomes were all assembled and assessed.
Overall, 1095 patients were critically infected
with COVID-19. Out of these, 239 patients (21.8%) received PPV. The study
cohort comprised 21.3% (51 out of 239 patients) with PBT. Invasive ventilation
was notably linked with reduced PBT odds, despite equal exposure to the same
modes of PPV in both groups.
The PBT people were much younger. Diabetes had a protective effect on
developing PBT, whereas the PO2/FIO2 ratio was inversely
linked with greater chances of getting PBT.
Patients infected with COVID-19 are more likely
to develop PBT. Invasive positive pressure ventilation but not the noninvasive
procedure was linked with less PBT. Also, postponing intubation does not appear
to minimize pulmonary barotrauma risk.
The International Journal of General Medicine
Pulmonary Barotrauma in COVID-19 Patients: Invasive versus Noninvasive Positive Pressure Ventilation
Shadi Hamouri et al.
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