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Role of obesity in catheter-associated bloodstream infections

Bloodstream infection Bloodstream infection
Bloodstream infection Bloodstream infection

For summarizing the existing evidences on the connection between obesity and bloodstream infections risk, a systematic review and meta-analysis was carried out.

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Key take away

Overweight, obesity and severe obesity are significantly linked with a greater risk of catheter-associated bloodstream infections.

Background

For summarizing the existing evidences on the connection between obesity and bloodstream infections risk, a systematic review and meta-analysis was carried out.

Method

Databases like PubMed, Web of Science, EMBASE, and MEDLINE were searched for the relevant studies published before January 2022. Utilizing a random-effects model, a meta-analysis was carried out.

Result

In total, 5 articles were incorporated. Volunteers with body mass index  ≥ 25 kg/m2  had an elevated risk of catheter-linked bloodstream infection (Odds Ratio [OR] 1.75) in the overall analysis. Additional  studies revealed that people with overweight, obesity and severe obesity were more susceptible to develop catheter-connected bloodstream infections (OR 1.51 [1.10–2.08], OR 1.43 [1.12–1.82] and OR 2.74 [1.85–4.05], respectively).

Conclusion

There is a close connection between obesity and a higher risk of bloodstream infections linked with catheter use. In clinical work, it is crucial to pay close attention to the risks and prognosis of obese people undergoing vascular catheterization.

Source:

Antimicrobial Resistance & Infection Control

Article:

Obesity and the risk of catheter-related bloodstream infection: a systematic review and meta-analysis

Authors:

Satish S.C. Rao et al.

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